Tamoxifen induces hepatocellular carcinoma in rat liver: A 1-year study with two antiestrogens

Author:

Hirsimäki Pirkko,Hirsimäki Yrjö,Nieminen Lauri,Payne Bobby Joe

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Reference9 articles.

1. Cameron R, Imaida K, Tsuda H, Ito N (1982) Promotive effects of steroids and bile acids on hepatocarcinogenesis initiated by diethylnitrosamine. Cancer Res 42: 2426–2428

2. Di Salle E, Zaccheo T, Ornati G (1990) Antiestrogenic and antitumor properties of the new triphenylethylene derivative toremifene in the rat. J Steroid Biochem Mol Biol 36: 203–206

3. Furr BJA, Jordan VC (1984) The pharmacology and clinical uses of tamoxifen. Pharmacol Ther 25: 127–205

4. Furr BJ, Patterson JS, Richardson DN, Slater SR, Wakeling AE (1979) Tamoxifen. In Goldberg M (ed) Biochemical properties of drug substances, vol 2. pp 355–399

5. Ghia M, Mereto E (1989) Induction and promotion of γ-glutamyltranspeptidase-positive foci in the liver of female rats treated with ethinyl estradiol, clomiphene, tamoxifen and their associations. Cancer Lett 46: 195–202

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