Sparse sampling for assessment of drug exposure in toxicological studies

Author:

Burtin P.,Mentre F.,van Bree J.,Steimer J. L.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference9 articles.

1. Tse F.L.S. (1995): Pharmacokinetics in drug discovery and development: nonclinical studies. In: Welling P.G., Tse F.L.S. (Eds) Pharmacokinetics. Regulatory, Industrial, Academic Perspectives. New York, Marcel Dekker, pp 311–334.

2. Rowland M., Aarons L. (1992): New Strategies in Drug Development and Clinical Evaluation: the Population Approach. Luxembourg, Commission of the European Communities.

3. van Bree J., Nedelman J., Steimer J.-L., et al. (1994): Application of sparse sampling approaches in rodent toxicokinetics: a prospective view. Drug Inf. J., 28, 263–279.

4. Nedelman J.R., Gibiansky E., Tse F.L.S., et al. (1993): Assessing drug exposure in rodent toxicity studies without satellite animals. J. Pharmacokinet. Biopharm., 21, 323–334.

5. Sheiner L.B., Grasela T.H. (1991): An introduction to mixed effect modeling: concepts, definitions, and justification. J. Pharmacokinet. Biopharm., 19, 25S-36S.

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