Metabolism of morphine and codeine by guinea-pig liver microsomal preparations and by rats

Author:

Phillipson J. David,El-Dabbas Samia W.,Gorrod John W.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference26 articles.

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2. Yeh S.Y., Goiodetzky C.W. and Kiebs H.A. (1977): Isolation and identification of morphine 3- and 6-glucuronides, morphine 3,6-diglucuronide, morphine 3-ethereal sulphate, nor-morphine and nor-morphine 6-glucuronide as morphine metabolites in humans. J. Pharm. Sci.,66, 1288–1293.

3. Elison C. and Elliott H.W. (1964): Studies in the enzymatic N- and O-demethylation of narcotic analgesics and evidence for the formation of codeine from morphine in rats and dogs. J. Pharmac. Exp. Ther.,144, 265–275.

4. Boerner U. and Abbott S. (1973): New observations in the metabolism of morphine, the formation of codeine from morphine in man. Experientia,29, 180–181.

5. Boerner U., Roe R.L. and Becker C.E. (1974): Detection, isolation and characterisation of nor-morphine and nor-codeine as morphine metabolites in man. J. Pharm. Pharmac,26, 393–398.

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