White paper on peanut allergy – part 1: Epidemiology, burden of disease, health economic aspects

Author:

Lange Lars,Klimek Ludger,Beyer Kirsten,Blümchen Katharina,Novak Natalija,Hamelmann Eckard,Bauer Andrea,Merk Hans,Rabe Uta,Jung Kirsten,Schlenter Wolfgang,Ring Johannes,Chaker Adam,Wehrmann Wolfgang,Becker Sven,Mülleneisen Norbert,Nemat Katja,Czech Wolfgang,Wrede Holger,Brehler Randolf,Fuchs Thomas,Jakob Thilo,Ankermann Tobias,Schmidt Sebastian M.,Gerstlauer Michael,Zuberbier Torsten,Spindler Thomas,Vogelberg Christian

Abstract

AbstractPeanuts are Leguminosae, commonly known as the legume or pea family, and peanut allergy is among the most common food allergies and the most common cause of fatal food reactions and anaphylaxis.The prevalence of peanut allergy increased 3.5-fold over the past two decades reaching 1.4–2% in Europe and the United States. The reasons for this increase in prevalence are likely multifaceted. Sensitization via the skin appears to be associated with the development of peanut allergy and atopic eczema in infancy is associated with a high risk of developing peanut allergy.Until recently, the only possible management strategy for peanut allergy was strict allergen avoidance and emergency treatment including adrenaline auto-injector in cases of accidental exposure and reaction.This paper discusses the various factors that impact the risks of peanut allergy and the burden of self-management on peanut-allergic children and their caregivers.

Funder

Universitätsklinikum Carl Gustav Carus Dresden an der Technischen Universität Dresden

Publisher

Springer Science and Business Media LLC

Subject

Immunology and Allergy

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