Determination of specific monoclonal antibody secretion rate during very slow hybridoma growth

Author:

Flickinger M. C.,Goebel N. K.,Bohn M. A.

Publisher

Springer Science and Business Media LLC

Subject

General Medicine,Bioengineering,Biotechnology,Applied Microbiology and Biotechnology,Biotechnology

Reference33 articles.

1. Griffiths, J. B.: Overview of cell culture systems and their scale up. In: Spier, R. E.; Griffiths, J. B. (Eds.): Animal Cell Biotechnology, vol. 3, pp. 179?221. Academic Press 1988

2. Berg, G. J.; Bodeker, B. G. D.: Employing a ceramic matrix for the immobilization of mammalian cells in culture. In: Spier, R. E.; Griffiths, J. B. (Eds.): Animal Cell Biotechnology, vol. 3, pp. 322?336. Academic Press 1988

3. Tolbert, W. R.; Feder, J; Lewis, C. Jr.: Static culture maintenance system. U.S. Patent 4, 537, 860. August 27, 1985

4. Feder, J.: The development of large-scale animal cell perfusion culture systems. Adv. Biotechnol. Proc. 7 (1988) 125?152

5. Takazawa, Y; Tokashiki, M.; Hamamoto, K.; Muratrami, H.: High cell density perfusion culture of hybridoma cells recycling high molecular weight components. Cytotechnol. 1 (1988) 171?178

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