Impact of Hypoxia-Related Tumor Acidosis on Cytotoxicity of Different Chemotherapeutic Drugs In Vitro and In Vivo

Author:

Thews Oliver,Riemann Anne,Nowak Martin,Gekle Michael

Publisher

Springer New York

Reference14 articles.

1. Teicher BA, Holden SA, al Achi A et al (1990) Classification of antineoplastic treatments by their differential toxicity toward putative oxygenated and hypoxic tumor subpopulations in vivo in the FSaIIC murine fibrosarcoma. Cancer Res 50:3339–3344

2. Fang J, Nakamura H, Iyer AK (2007) Tumor-targeted induction of oxystress for cancer therapy. J Drug Target 15:475–486

3. Chaplin DJ, Horsman MR, Trotter MJ et al (1998) Therapeutic significance of microenvironmental factors. In: Molls M, Vaupel P (eds) Blood perfusion and microenvironment of human tumors. Springer, Berlin, pp 131–143

4. Teicher BA (1994) Hypoxia and drug resistance. Cancer Metastasis Rev 13:139–168

5. Sauvant C, Nowak M, Wirth C et al (2008) Acidosis induces multi-drug resistance in rat prostate cancer cells (AT1) in vitro and in vivo by increasing the activity of the p-glycoprotein via activation of p38. Int J Cancer 123:2532–2542

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