Associations Among Sex, Cognitive Ability, and Autism Symptoms in Individuals with Down Syndrome

Author:

del Hoyo Soriano LauraORCID,Sterling Audra,Edgin Jamie,Hamilton Debra R.,Berry-Kravis Elizabeth,Dimachkie Nunnally Amanda,Thurman Angela John,Abbeduto Leonard

Abstract

AbstractThis study explores sex-differences in (a) rates and profiles of autism symptoms as well as in (b) the contribution of intellectual quotient (IQ) to autism symptom presentation in Down syndrome (DS). Participants were 40 males and 38 females with DS, aged 6 to 23 years. Autism symptoms were rated through the Autism Diagnostic Observation Schedule-Second Edition (ADOS-2). Results show no sex differences in the ADOS-2 Calibrated Severity Scores (CSS). However, only females with DS who are classified as DS-Only have higher scores on verbal IQ than those classified as DS + autism. Furthermore, associations between IQ and all CSSs are found for females, but not for males. Findings suggest that verbal cognition may play differential roles for females and males with DS.

Funder

National Institute of Health

Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Center for Advancing Translational Sciences

Publisher

Springer Science and Business Media LLC

Subject

Developmental and Educational Psychology

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Co‐occurring conditions in Down syndrome: Findings from a clinical database;American Journal of Medical Genetics Part C: Seminars in Medical Genetics;2023-10-24

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