Pulsatile glucagon has greater hyperglycaemic, lipolytic and ketogenic effects than continuous hormone delivery in man: effect of age-Reference-Cited by-同舟云学术

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Pulsatile glucagon has greater hyperglycaemic, lipolytic and ketogenic effects than continuous hormone delivery in man: effect of age

Published:1990-05 Issue:5 Volume:33 Page:272-277
ISSN:0012-186X
Container-title:Diabetologia
language:en
Short-container-title:Diabetologia

Author:

Paolisso G.,Buonocore S.,Gentile S.,Sgambato S.,Varricchio M.,Scheen A.,D'Onofrio F.,Lef�bvre P. J.

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://link.springer.com/content/pdf/10.1007/BF00403320.pdf

Reference26 articles.

1. Goodner CJ, Walike BC, Koerker DJ, Ensinck JW, Brown AC, Chideckel E, Palmer JC, Kalnasy L (1977) Insulin, glucagon and glucose exhibit synchronous sustained oscillations in fasting monkeys. Science 195: 177?179

2. Lang DA, Matthews DR, Peto J, Turner RC (1979) Cyclic oscillations of basal plasma glucose and insulin concentrations in human beings. N Engl J Med 301: 1023?1027

3. Lefèbvre PJ, Paolisso G, Scheen AJ, Henquin JC (1987) Pulsatility of insulin and glucagon release: physiological significance and pharmacological implications. Diabetologia 30: 443?452

4. Matthews DR, Naylor BA, Jones RG, Ward GM, Turner RC (1983) Pulsatile insulin has greater hypoglycemic effect than continuous delivery. Diabetes 32: 617?621

5. Paolisso G, Sgambato S, Passariello N, Scheen AJ, D'Onofrio F, Lefèbvre PJ (1987) Greater efficacy of pulsatile insulin in type I diabetics critically depends on plasma glucagon levels. Diabetes 36: 566?570

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