Monoclonal antibodies to the thyrotropin receptor: the identification of blocking and stimulating antibodies

Author:

Valente W. A.,Yavin Z.,Yavin E.,Grollman E. F.,Schneider M.,Rotella C. M.,Zonefrati R.,Toccafondi R. S.,Kohn L. D.

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

Reference48 articles.

1. Yavin E., Yavin Z., Schneider M.D., Kohn L.D. Monoclonal antibodies to the thyrotropin receptor; implications for receptor structure and the action of autoantibodies in Graves’ disease. Proc. Natl. Acad. Sci. USA 78: 3180, 1981.

2. Yavin E., Yavin Z., Schneider M.D., Kohn L.D. Monoclonal antibodies to the thyrotropin receptor: interaction with thyroid membranes on solid surfaces and on thyroid cells. In: Fellows R.E., Eisenbarth G. (Eds.), monoclonal Antibodies in endocrine research. Raven Press, New York, 1981, p. 53.

3. Yavin E., Yavin Z., Schneider M.D., Kohn L.D. Monoclonal antibodies as probes for ligand-receptor interactions: studies of the thyrotropin receptor. In: Owen D. (Ed.), Cold Spring Harbor Symposium on Monoclonal Antibodies. Cold Spring Harbor Laboratories, New York, 1981. (in press).

4. Winand R.J., Kohn L.D. Thyrotropin effects on thyroid cells in culture; effects of trypsin on the thyrotropin receptor and on thyrotropin-mediated cyclic 3″:5′ — AMP changes. J. Biol. Chem. 250: 6534, 1975.

5. Tate R.L., Schwartz H.I., Holmes J.M., Kohn L.D., Winand R.J. Thyrotropin receptors in thyroid plasma membranes. Characteristics of thyrotropin binding and solubilization of thyrotropin receptor activity by trypsin digestion. J. Biol. Chem. 250: 6509, 1975.

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