Author:
Green Damian J.,Bensinger William I.
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology,Hematology
Reference61 articles.
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5. • Barlogie B, Kyle RA, Anderson KC, et al. Standard chemotherapy compared with high-dose chemoradiotherapy for multiple myeloma: final results of phase III US Intergroup Trial S9321. J Clin Oncol. 2006;24(6):929–36. This trial was primarily designed to test timing of an autologous stem cell transplant. A small number of patients with HLA matched donors had allografts with very high transplant related mortality which closed that arm. With longer follow-up, however, the survival of the allograft arm exceeded the autograft survival, thus underscoring the potential immunologic effect against myeloma.
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