Therapy Resistance and Disease Progression in CML: Mechanistic Links and Therapeutic Strategies
Author:
Funder
National Medical Research Council Singapore
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology,Hematology
Link
https://link.springer.com/content/pdf/10.1007/s11899-022-00679-z.pdf
Reference167 articles.
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2. •• Mahon FX, Rea D, Guilhot J, Guilhot F, Huguet F, Nicolini F, Legros L, Charbonnier A, Guerci A, Varet B, Etienne G, Reiffers J, Rousselot P. Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial. Lancet Oncol. 2010;11(11):1029–35. https://doi.org/10.1016/S1470-2045(10)70233-3S1470-2045(10)70233-3. Pivotal study demonstrating possibility of TFR.
3. • Ross DM, Hughes TP. Treatment-free remission in patients with chronic myeloid leukaemia. Nat Rev Clin Oncol. 2020;17(8):493–503. https://doi.org/10.1038/s41571-020-0367-1. Recent and comprehensive review on TFR.
4. Quintas-Cardama A, Kantarjian HM, Cortes JE. Mechanisms of primary and secondary resistance to imatinib in chronic myeloid leukemia. Cancer Control. 2009;16(2):122–31. https://doi.org/10.1177/107327480901600204.
5. Shanmuganathan N, Pagani IS, Ross DM, Park S, Yong ASM, Braley JA, Altamura HK, Hiwase DK, Yeung DT, Kim DW, Branford S, Hughes TP. Early BCR-ABL1 kinetics are predictive of subsequent achievement of treatment-free remission in chronic myeloid leukemia. Blood. 2021;137(9):1196–207. https://doi.org/10.1182/blood.2020005514. Important study relating early BCR-ABL1 kinetics to distal TKI responses.
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