New Approaches to Treating Challenging Subtypes of ALL in AYA Patients

Author:

Prescott Kevin,Jacobs Michael,Stock Wendy,Wynne Joseph

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,Hematology

Reference88 articles.

1. • Siegel SE, Stock W, Johnson RH, Advani A, Muffly L, Douer D, et al. Pediatric-inspired treatment regimens for adolescents and young adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: a review. JAMA Oncol. 2018;4(5):725–34. https://doi.org/10.1001/jamaoncol.2017.5305This review summarizes strong retrospective data supporting the use of pediatric inspired chemotherapy regimens in the treatment of AYA ALL.

2. •• DeAngelo DJ, Stevenson KE, Dahlberg SE, Silverman LB, Couban S, Supko JG, et al. Long-term outcome of a pediatric-inspired regimen used for adults aged 18-50 years with newly diagnosed acute lymphoblastic leukemia. Leukemia. 2015;29(3):526–34. https://doi.org/10.1038/leu.2014.229Prospective trial that shows improved survival with pediatric inspired chemotherapy regimens for AYA patients with newly diagnosed ALL.

3. •• Toft N, Birgens H, Abrahamsson J, Griskevicius L, Hallbook H, Heyman M, et al. Results of NOPHO ALL2008 treatment for patients aged 1-45 years with acute lymphoblastic leukemia. Leukemia. 2018;32(3):606–15. https://doi.org/10.1038/leu.2017.265Prospective trial that shows improved survival with pediatric inspired chemotherapy regimens for AYA patients with newly diagnosed ALL.

4. •• Stock W, Luger SM, Advani AS, Yin J, Harvey RC, Mullighan CG, et al. A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403. Blood. 2019;133(14):1548–59. https://doi.org/10.1182/blood-2018-10-881961Prospective trial that shows improved survival with pediatric inspired chemotherapy regimens for AYA patients with newly diagnosed ALL.

5. Rizzari C, Putti MC, Colombini A, Casagranda S, Ferrari GM, Papayannidis C, et al. Rationale for a pediatric-inspired approach in the adolescent and young adult population with acute lymphoblastic leukemia, with a focus on asparaginase treatment. Hematol Rep. 2014;6(3):5554. https://doi.org/10.4081/hr.2014.5554.

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