A triterpenediol from Boswellia serrata induces apoptosis through both the intrinsic and extrinsic apoptotic pathways in human leukemia HL-60 cells

Author:

Bhushan Shashi,Kumar Ajay,Malik Fayaz,Andotra Samar Singh,Sethi Vijay Kumar,Kaur Indu Pal,Taneja Subhash Chandra,Qazi Ghulam Nabi,Singh Jaswant

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Biochemistry (medical),Cell Biology,Clinical Biochemistry,Pharmaceutical Science,Pharmacology

Reference49 articles.

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3. Safayhi H, Mack T, Sabieraj J, Anazodo MI, Subramanian LR, Ammon HP (1992) Boswellic acids: novel, specific, non-redox inhibitors of 5-lipoxygenase. J Pharmacol Exp Ther 26:1143–1146

4. Hoernlein RF, Orlikowsky TH, Zehrer C et al. (1999) Acetyl-11-keto-beta-boswellic acid induce apoptosis in HL-60 and CCRF-CEM cells and inhibit topoisomerase-I. J Pharmacol Exp Ther 288:613–619

5. Mahajan B, Taneja SC, Sethi VK, Dhar KL (1995) Two triterpenoids from Boswellia serrata gum resin. Phytochemistry 39:453–455

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