A novel oxaliplatin derivative, Ht-2, triggers mitochondrion-dependent apoptosis in human colon cancer cells

Author:

Xing Yingying,Bao Weiwei,Fan Xiaobo,Liu Kunmei,Li Xiaokang,Xi Tao

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Biochemistry, medical,Cell Biology,Clinical Biochemistry,Pharmaceutical Science,Pharmacology

Reference25 articles.

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3. Johnson SW, Laub PB, Beesley JS, Ozols RF, Hamilton TC (1997) Increased platinum-DNA damage tolerance is associated with cisplatin resistance and cross-resistance to various chemotherapeutic agents in unrelated human ovarian cancer cell lines. Cancer Res 57:850–856

4. Montana AM, Batalla C (2009) The rational design of anticancer platinum complexes: the importance of the structure–activity relationship. Curr Med Chem 16:2235–2260

5. Kelland LR (2000) Preclinical perspectives on platinum resistance. Drugs 59(Suppl 4):1–8 discussion 37-38

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