20(S)-25-methoxyl-dammarane-3β, 12β, 20-triol negatively regulates activation of STAT3 and ERK pathways and exhibits anti-cancer effects in HepG2 cells-Reference-Cited by-同舟云学术

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20(S)-25-methoxyl-dammarane-3β, 12β, 20-triol negatively regulates activation of STAT3 and ERK pathways and exhibits anti-cancer effects in HepG2 cells

Published:2017-09-01 Issue:11 Volume:22 Page:1404-1418
ISSN:1360-8185
Container-title:Apoptosis
language:en
Short-container-title:Apoptosis

Author:

Ai Hui-Han,Zhou Zi-Long,Sun Lu-Guo,Yang Mei-Ting,Li Wei,Yu Chun-Lei,Song Zhen-Bo,Huang Yan-Xin,Wu Yin,Liu Lei,Yang Xiao-Guang,Zhao Yu-Qing,Bao Yong-Li,Li Yu-Xin

Funder

National Natural Science Foundation of China

National Key New Drug Creation and Manufacturing Program of Ministry of Science and Technology

Grant of Administration of Traditional Chinese Medicine of Jilin Province

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Biochemistry (medical),Cell Biology,Clinical Biochemistry,Pharmaceutical Science,Pharmacology

Link

http://link.springer.com/article/10.1007/s10495-017-1416-9/fulltext.html

Reference35 articles.

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2. Middleton K, Jones J, Lwin Z, Coward JI (2014) Interleukin-6: an angiogenic target in solid tumours. Crit Rev Oncol Hematol 89(1):129–139. doi: 10.1016/j.critrevonc.2013.08.004

3. Guo Y, Xu F, Lu T, Duan Z, Zhang Z (2012) Interleukin-6 signaling pathway in targeted therapy for cancer. Cancer Treat Rev 38(7):904–910. doi: 10.1016/j.ctrv.2012.04.007

4. He G, Dhar D, Nakagawa H, Font-Burgada J, Ogata H, Jiang Y, Shalapour S, Seki E, Yost SE, Jepsen K, Frazer KA, Harismendy O, Hatziapostolou M, Iliopoulos D, Suetsugu A, Hoffman RM, Tateishi R, Koike K, Karin M (2013) Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling. Cell 155(2):384–396. doi: 10.1016/j.cell.2013.09.031

5. Ohishi W, Cologne JB, Fujiwara S, Suzuki G, Hayashi T, Niwa Y, Akahoshi M, Ueda K, Tsuge M, Chayama K (2014) Serum interleukin-6 associated with hepatocellular carcinoma risk: a nested case-control study. Int J Cancer 134(1):154–163. doi: 10.1002/ijc.28337

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