Centchroman induces redox-dependent apoptosis and cell-cycle arrest in human endometrial cancer cells

Author:

Shyam Hari,Singh Neetu,Kaushik Shweta,Sharma Ramesh,Balapure Anil K.

Funder

Central Drug Research Institute

Indian Council of Medical Research

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Biochemistry (medical),Cell Biology,Clinical Biochemistry,Pharmaceutical Science,Pharmacology

Reference32 articles.

1. Jordan VC (1988) Tamoxifen and endometrial cancer. Lancet 2:1019

2. Anand N, Ray S (1977) Centchroman–a post-coital contraceptive agent. Indian J Exp Biol 15:1130–1142

3. Kamboj VP, Setty BS, Chandra H, Roy SK, Kar AB (1977) Biological profile of centchroman-a new post-coital contraceptive. Indian J Exp Biol 15:1144–1150

4. Srivastava S, Sharma R, Balapure AK (2004) Morphological and biochemical basis of centchroman as a novel antineoplastic agent in MCF-7 human breast cancer cells. Indian J Pharmacol 36:238–243

5. Nigam M, Ranjan V, Srivastava S, Sharma R, Balapure AK (2008) Centchroman induces G0/G1 arrest and caspase-dependent apoptosis involving mitochondrial membrane depolarization in MCF-7 and MDA MB-231 human breast cancer cells. Life Sci 82:577–590

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