Regulatory T cells: present facts and future hopes

Author:

Becker Christian,Stoll Sabine,Bopp Tobias,Schmitt Edgar,Jonuleit Helmut

Publisher

Springer Science and Business Media LLC

Subject

Microbiology (medical),Immunology,General Medicine,Immunology and Allergy

Reference105 articles.

1. Sprent J (1995) Central tolerance of T cells. Int Rev Immunol 13:95–105

2. Mason D (1998) A very high level of crossreactivity is an essential feature of the T-cell receptor. Immunol Today 19:395–404

3. Sakaguchi S, Fukuma K, Kuribayashi K, Masuda T (1985) Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease. J Exp Med 161:72–87

4. Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M (1995) Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 155:1151–1164

5. Suri-Payer E, Amar AZ, Thornton AM, Shevach EM (1998) CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J Immunol 160:1212–1218

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