Simultaneous analysis of multiple T helper subsets in leprosy reveals distinct patterns of Th1, Th2, Th17 and Tregs markers expression in clinical forms and reactional events

Author:

Azevedo Michelle de Campos Soriani,Marques Heloisa,Binelli Larissa Sarri,Malange Mariana Silva Vieira,Devides Amanda Carreira,Silva Eliane Aparecida,Fachin Luciana Raquel Vincenzi,Ghidella Cassio Cesar,Soares Cleverson Teixeira,Garlet Gustavo Pompermaier,Rosa Patrícia Sammarco,Belone Andrea de Farias Fernandes,Trombone Ana Paula Favaro

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo - FAPESP

Publisher

Springer Science and Business Media LLC

Subject

Microbiology (medical),Immunology,General Medicine,Immunology and Allergy

Reference43 articles.

1. Scollard DM, Adams LB, Gillis TP, Krahenbuhl JL, Truman RW, Williams DL (2006) The continuing challenges of leprosy. Clin Microbiol Rev 19:338–381

2. World Health Organization (2015) Global leprosy update 2015: time for action, accountability and inclusion. Wkly Epidemiol Rec 91:405–420

3. Bratschi MW, Steinmann P, Wickenden A, Gillis TP (2015) Current knowledge on Mycobacterium leprae transmission: a systematic literature review. Lepr Rev 86:142–155

4. Ridley DS, Jopling WH (1966) Classification of leprosy according to immunity. a five-group system. Int J Lepr Other Mycobact Dis 34:255–273

5. Yamamura M, Wang XH, Ohmen JD, Uyemura K, Rea TH, Bloom BR, Modlin RL (1992) Cytokine patterns of immunologically mediated tissue damage. J Immunol 149:1470–1475

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