Pharmacokinetic analysis of metronomic capecitabine in refractory metastatic colorectal cancer patients-Reference-Cited by-同舟云学术

Pharmacokinetic analysis of metronomic capecitabine in refractory metastatic colorectal cancer patients

Published:2018-02-27 Issue:4 Volume:36 Page:709-714
ISSN:0167-6997
Container-title:Investigational New Drugs
language:en
Short-container-title:Invest New Drugs

Author:

Di Desidero Teresa,Orlandi Paola,Fioravanti Anna,Cremolini Chiara,Loupakis Fotios,Marmorino Federica,Antoniotti Carlotta,Masi Gianluca,Lonardi Sara,Bergamo Francesca,Zagonel Vittorina,Falcone Alfredo,Bocci Guido^ORCID

Funder

Istituto Toscano Tumori

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Link

http://link.springer.com/article/10.1007/s10637-018-0579-8/fulltext.html

Reference28 articles.

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3. Tabata T, Katoh M, Tokudome S, Hosakawa M, Chiba K, Nakajima M, Yokoi T (2004) Bioactivation of capecitabine in human liver: involvement of the cytosolic enzyme on 5′-deoxy-5-fluorocytidine formation. Drug Metab Dispos 32(7):762–767

4. Mercier C, Dupuis C, Blesius A, Fanciullino R, Yang CG, Padovani L, Giacometti S, Frances N, Iliadis A, Duffaud F, Ciccolini J (2009) Early severe toxicities after capecitabine intake: possible implication of a cytidine deaminase extensive metabolizer profile. Cancer Chemother Pharmacol 63(6):1177–1180

5. Camiener GW, Smith CG (1965) Studies of the enzymatic deamination of cytosine arabinoside. I Enzyme distribution and species specificity. Biochem Pharmacol 14(10):1405–1416

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