First clinical pharmacokinetic dose-escalation study of sagopilone, a novel, fully synthetic epothilone, in Japanese patients with refractory solid tumors-Reference-Cited by-同舟云学术

First clinical pharmacokinetic dose-escalation study of sagopilone, a novel, fully synthetic epothilone, in Japanese patients with refractory solid tumors

Published:2011-12-04 Issue:6 Volume:30 Page:2327-2333
ISSN:0167-6997
Container-title:Investigational New Drugs
language:en
Short-container-title:Invest New Drugs

Author:

Araki Kazuhiro,Kitagawa Koichi,Mukai Hirofumi,Mukohara Toru,Kodama Keiji,Ando Yuichi,Narabayashi Masaru,Minami Hironobu,Mera Kiyomi,Sasaki Yasutsuna

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Link

http://link.springer.com/content/pdf/10.1007/s10637-011-9773-7.pdf

Reference18 articles.

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3. Gerth K, Bedorf N, Hofle G et al (1996) Epothilons A and B: antifungal and cytotoxic compounds from Sorangium cellulosum (Myxobacteria). Production, physico-chemical and biological properties. J Antibiot (Tokyo) 49:560–563

4. Bollag DM, McQueney PA, Zhu J et al (1995) Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action. Cancer Res 55:2325–2333

5. Altmann KH, Bold G, Caravatti G et al (2000) Synthesis and biological evaluation of highly potent analogues of epothilones B and D. Bioorg Med Chem Lett 10:2765–2768

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