A phase I study of the investigational NEDD8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924) in patients with metastatic melanoma-Reference-Cited by-同舟云学术

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A phase I study of the investigational NEDD8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924) in patients with metastatic melanoma

Published:2016-04-08 Issue:4 Volume:34 Page:439-449
ISSN:0167-6997
Container-title:Investigational New Drugs
language:en
Short-container-title:Invest New Drugs

Author:

Bhatia Shailender,Pavlick Anna C.,Boasberg Peter,Thompson John A.,Mulligan George,Pickard Michael D.,Faessel Hélène,Dezube Bruce J.,Hamid Omid

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Link

http://link.springer.com/content/pdf/10.1007/s10637-016-0348-5.pdf

Reference45 articles.

1. Ciechanover A (2012) Intracellular protein degradation: from a vague idea through the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting. Neurodegener Dis 10(1–4):7–22

2. Shen M, Schmitt S, Buac D, Dou QP (2013) Targeting the ubiquitin-proteasome system for cancer therapy. Expert Opin Ther Targets 17(9):1091–1108

3. Esseltine DL, Mulligan G (2012) An historic perspective of proteasome inhibition. Semin Hematol 49(3):196–206

4. Bedford L, Lowe J, Dick LR, Mayer RJ, Brownell JE (2011) Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets. Nat Rev Drug Discov 10(1):29–46

5. Soucy TA, Dick LR, Smith PG, Milhollen MA, Brownell JE (2010) The NEDD8 conjugation pathway and its relevance in cancer biology and therapy. Genes Cancer 1(7):708–716

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