Synergistic effect of adavosertib and fimepinostat on acute myeloid leukemia cells by enhancing the induction of DNA damage-Reference-Cited by-同舟云学术

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Synergistic effect of adavosertib and fimepinostat on acute myeloid leukemia cells by enhancing the induction of DNA damage

Published:2023-12-12 Issue: Volume: Page:
ISSN:0167-6997
Container-title:Investigational New Drugs
language:en
Short-container-title:Invest New Drugs

Author:

Wang Yue,Lin Xingyu,Wang Yue,Wang Guan

Funder

National Natural Science Foundation of China

Projects of Jilin Province Science and Technology Development Plan

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Link

https://link.springer.com/content/pdf/10.1007/s10637-023-01415-x.pdf

Reference35 articles.

1. Bhansali RS, Pratz KW, Lai C (2023) Recent advances in targeted therapies in acute myeloid leukemia. J Hematol Oncol 16(1):29. https://doi.org/10.1186/s13045-023-01424-6

2. Matheson CJ, Backos DS, Reigan P (2016) Targeting WEE1 Kinase in Cancer. Trends Pharmacol Sci 37(10):872–881. https://doi.org/10.1016/j.tips.2016.06.006

3. Qi W, Xie C, Li C, Caldwell JT, Edwards H, Taub JW, Wang Y, Lin H, Ge Y (2014) CHK1 plays a critical role in the anti-leukemic activity of the wee1 inhibitor MK-1775 in acute myeloid leukemia cells. J Hematol Oncol 7:53. https://doi.org/10.1186/s13045-014-0053-9

4. Chen G, Zhang B, Xu H, Sun Y, Shi Y, Luo Y, Jia H, Wang F (2017) Suppression of Sirt1 sensitizes lung cancer cells to WEE1 inhibitor MK-1775-induced DNA damage and apoptosis. Oncogene 36(50):6863–6872. https://doi.org/10.1038/onc.2017.297

5. Hauge S, Macurek L (2019) p21 limits S phase DNA damage caused by the Wee1 inhibitor MK1775. 18(8):834–847. https://doi.org/10.1080/15384101.2019.1593649

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