Notoginsenoside R1 counteracts mesenchymal stem cell-evoked oncogenesis and doxorubicin resistance in osteosarcoma cells by blocking IL-6 secretion-induced JAK2/STAT3 signaling
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology,Oncology
Link
http://link.springer.com/content/pdf/10.1007/s10637-020-01027-9.pdf
Reference34 articles.
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2. Anderson ME (2016) Update on Survival in Osteosarcoma. Orthop Clin North Am 47:283–292. https://doi.org/10.1016/j.ocl.2015.08.022
3. Marina NM, Smeland S, Bielack SS et al (2016) Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial. Lancet Oncol 17:1396–1408. https://doi.org/10.1016/S1470-2045(16)30214-5
4. O'Kane GM, Cadoo KA, Walsh EM et al (2015) Perioperative chemotherapy in the treatment of osteosarcoma: a 26-year single institution review. Clin Sarcoma Res 5:17. https://doi.org/10.1186/s13569-015-0032-0
5. Zheng Y, Wang G, Chen R, Hua Y, Cai Z (2018) Mesenchymal stem cells in the osteosarcoma microenvironment: their biological properties, influence on tumor growth, and therapeutic implications. Stem Cell Res Ther 9:22. https://doi.org/10.1186/s13287-018-0780-x
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