Paclitaxel in self-micro emulsifying formulations: oral bioavailability study in mice

Author:

Oostendorp Roos L.,Buckle T.,Lambert G.,Garrigue J. S.,Beijnen J. H.,Schellens J. H. M.,van Tellingen O.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Reference26 articles.

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2. Rowinsky EK, Wright M, Monsarrat B, Donehower RC (1994) Clinical pharmacology and metabolism of Taxol (paclitaxel): update 1993. Ann Oncol 5(Suppl 6):S7–S16, S7–16

3. Dorr RT (1994) Pharmacology and toxicology of Cremophor EL diluent. Ann Pharmacother 28:S11–S14

4. Sparreboom A, van Tellingen O, Nooijen WJ, Beijnen JH (1996) Nonlinear pharmacokinetics of paclitaxel in mice results from the pharmaceutical vehicle Cremophor EL. Cancer Res 56:2112–2115

5. van Tellingen O, Huizing MT, Panday VR, Schellens JH, Nooijen WJ, Beijnen JH (1999) Cremophor EL causes (pseudo-) non-linear pharmacokinetics of paclitaxel in patients. Br J Cancer 81:330–335

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