A phase 1b study of the allosteric extracellular FGFR2 inhibitor alofanib in patients with pretreated advanced gastric cancer-Reference-Cited by-同舟云学术

A phase 1b study of the allosteric extracellular FGFR2 inhibitor alofanib in patients with pretreated advanced gastric cancer

Published:2023-03-13 Issue:2 Volume:41 Page:324-332
ISSN:0167-6997
Container-title:Investigational New Drugs
language:en
Short-container-title:Invest New Drugs

Author:

Tsimafeyeu Ilya,Statsenko Galina,Vladimirova Liubov,Besova Natalia,Artamonova Elena,Raskin Grigory,Rykov Ivan,Mochalova Anastasia,Utyashev Igor,Gorbacheva Svetlana,Kazey Vasily,Gavrilova Evgenia,Dragun Nadezhda,Moiseyenko Vladimir,Tjulandin Sergei

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Link

https://link.springer.com/content/pdf/10.1007/s10637-023-01340-z.pdf

Reference23 articles.

1. Figueiredo C, Camargo MC, Leite M, Fuentes-Pananá EM, Rabkin CS, Machado JC (2017) Pathogenesis of Gastric Cancer: Genetics and Molecular Classification. Curr Top Microbiol Immunol 400:277–304. https://doi.org/10.1007/978-3-319-50520-6_12.Erratum.In:CurrTopMicrobiolImmunol.2017;400:E1

2. Seo S, Park SJ, Ryu MH et al (2017) Prognostic impact of fibroblast growth factor receptor 2 gene amplification in patients receiving fluoropyrimidine and platinum chemotherapy for metastatic and locally advanced unresectable gastric cancers. Oncotarget 8(20):33844–33854

3. Kim HS, Kim JH, Jang HJ (2019) Pathologic and prognostic impacts of FGFR2 amplification in gastric cancer: a meta-analysis and systemic review. J Cancer 10(11):2560–2567

4. Ahn S, Lee J, Hong M et al (2016) FGFR2 in gastric cancer: protein overexpression predicts gene amplification and high H-index predicts poor survival. Mod Pathol 29:1095–1103

5. Schrumpf T, Behrens HM, Haag J, Krüger S, Röcken C (2022) FGFR2 overexpression and compromised survival in diffuse-type gastric cancer in a large central European cohort. PLoS One 17(2)

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