Phase I study of cediranib, an oral VEGFR inhibitor, in combination with selumetinib, an oral MEK inhibitor, in patients with advanced solid malignancies-Reference-Cited by-同舟云学术

Phase I study of cediranib, an oral VEGFR inhibitor, in combination with selumetinib, an oral MEK inhibitor, in patients with advanced solid malignancies

Published:2021-09-13 Issue:1 Volume:40 Page:115-123
ISSN:0167-6997
Container-title:Investigational New Drugs
language:en
Short-container-title:Invest New Drugs

Author:

Hubbard Joleen M.,Yin Jun,Schenk Erin L.,Qin Rui,Reid Joel M.,Strand Carrie,Fiskum Jack,Menefee Michael,Lin Grace,Doyle L. Austin,Ivy Percy,Erlichman Charles,Adjei Alex,Haluska Paul,Costello Brian A.^ORCID

Funder

mayo clinic u01

mayo clinic um1

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Link

https://link.springer.com/content/pdf/10.1007/s10637-021-01175-6.pdf

Reference53 articles.

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3. Yarden Y, Sliwkowski MX (2001) Untangling the ErbB signalling network. Nat Rev Mol Cell Biol 2(2):127–137. https://doi.org/10.1038/35052073

4. Wedge SR et al (2005) AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer. Cancer Res 65(10):4389–4400. https://doi.org/10.1158/0008-5472.can-04-4409

5. Garland LL et al (2011) Phase II Study of Cediranib in Patients with Malignant Pleural Mesothelioma: SWOG S0509. J Thorac Oncol 6(11):1938–1945. https://doi.org/10.1097/jto.0b013e318229586e

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