The proportion of North American cancer trials that evaluate novel targets
Author:
Funder
CIHR
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology,Oncology
Link
https://link.springer.com/content/pdf/10.1007/s10637-020-00971-w.pdf
Reference14 articles.
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2. Carlisle B, Demko N, Freeman G, Hakala A, MacKinnon N, Ramsay T, Hey S, London AJ, Kimmelman J (2016) Benefit, risk, and outcomes in drug development: a systematic review of Sunitinib. J Natl Cancer Inst 108(1). https://doi.org/10.1093/jnci/djv292
3. Mattina J, Carlisle B, Hachem Y, Fergusson D, Kimmelman J (2017) Inefficiencies and patient burdens in the development of the targeted Cancer drug Sorafenib: a systematic review. PLoS Biol 15(2):e2000487. https://doi.org/10.1371/journal.pbio.2000487
4. Bertolini F, Sukhatme VP, Bouche G (2015) Drug repurposing in oncology—patient and health systems opportunities. Nat Rev Clin Oncol 12:732–742. https://doi.org/10.1038/nrclinonc.2015.169
5. Leroux JC (2018) The novelty bubble. J Control Release 278:140–141. https://doi.org/10.1016/j.jconrel.2018.03.032
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