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Eltrombopag treatment promotes platelet recovery and reduces platelet transfusion for patients with post-transplantation thrombocytopenia

  • Published:2020-06-09 Issue:11 Volume:99 Page:2679-2687
  • ISSN:0939-5555
  • Container-title:Annals of Hematology
  • language:en
  • Short-container-title:Ann Hematol

Author:

Gao Fei,Zhou Xiaoyu,Shi Jimin,Luo Yi,Tan Yamin,Fu Huarui,Lai Xiaoyu,Yu Jian,Huang He,Zhao YanminORCID

Funder

National Natural Science Foundation of China

Key R&D Program of Zhejiang Province

Publisher

Springer Science and Business Media LLC

Subject

Hematology,General Medicine

Reference39 articles.

1. Dominietto A, Raiola AM, van Lint MT, Lamparelli T, Gualandi F, Berisso G, Bregante S, Frassoni F, Casarino L, Verdiani S, Bacigalupo A (2001) Factors influencing haematological recovery after allogeneic haemopoietic stem cell transplants: graft-versus-host disease, donor type, cytomegalovirus infections and cell dose. Br J Haematol 112(1):219–227. https://doi.org/10.1046/j.1365-2141.2001.02468.x

2. Akahoshi Y, Kanda J, Gomyo A, Hayakawa J, Komiya Y, Harada N, Kameda K, Ugai T, Wada H, Ishihara Y, Kawamura K, Sakamoto K, Sato M, Terasako-Saito K, Kimura SI, Kikuchi M, Nakasone H, Kako S, Kanda Y (2016) Risk factors and impact of secondary failure of platelet recovery after allogeneic stem cell transplantation. Biol Blood Marrow Transplant 22(9):1678–1683. https://doi.org/10.1016/j.bbmt.2016.06.003

3. Vamvakas EC, Blajchman MA (2009) Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention. Blood 113(15):3406–3417. https://doi.org/10.1182/blood-2008-10-167643

4. Cheng G, Saleh MN, Marcher C, Vasey S, Mayer B, Aivado M, Arning M, Stone NL, Bussel JB (2011) Eltrombopag for management of chronic immune thrombocytopenia (RAISE): a 6-month, randomised, phase 3 study. Lancet 377(9763):393–402. https://doi.org/10.1016/S0140-6736(10)60959-2

5. Wong RSM, Saleh MN, Khelif A, Salama A, Portella MSO, Burgess P, Bussel JB (2017) Safety and efficacy of long-term treatment of chronic/persistent ITP with eltrombopag: final results of the EXTEND study. Blood 130(23):2527–2536. https://doi.org/10.1182/blood-2017-04-748707
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