Safe and successful teclistamab treatment in very elderly multiple myeloma (MM) patients: a case report and experience from a total of three octogenarians

Author:

Dieterle Martin Philipp,Mostufi-Zadeh-Haghighi Gila,Kus Jan Wilhelm,Wippel Christopher,Brugger Zacharias,Miething Cornelius,Wäsch Ralph,Engelhardt MonikaORCID

Funder

Universitätsklinikum Freiburg

Publisher

Springer Science and Business Media LLC

Subject

Hematology,General Medicine

Reference10 articles.

1. Shrivastava T, Van Rhee F, Al Hadidi S (2023) Targeting B cell maturation antigen in patients with multiple myeloma: current perspectives. Onco Targets Ther 16:441–464. https://doi.org/10.2147/ott.s370880

2. Moreau P, van de Donk NWCJ, Delforge M et al (2023) Comparative Efficacy of teclistamab versus current treatments in real-world clinical practice in the prospective LocoMMotion study in patients with triple-class-exposed relapsed and/or refractory multiple myeloma. Adv Ther 40:2412–2425. https://doi.org/10.1007/s12325-023-02480-7

3. Usmani SZ, Garfall AL, van de Donk NWCJ et al (2021) Teclistamab, a B-cell maturation antigen × CD3 bispecific antibody, in patients with relapsed or refractory multiple myeloma (MajesTEC-1): a multicentre, open-label, single-arm, phase 1 study. Lancet 398:665–674. https://doi.org/10.1016/S0140-6736(21)01338-6

4. Mateos MV, Chari A, Usmani SZ et al (2023) Comparative efficacy of teclistamab versus physician’s choice of therapy in the long-term follow-up of APOLLO, POLLUX, CASTOR, and EQUULEUS clinical trials in patients with triple-class exposed relapsed or refractory multiple myeloma. Clin Lymphoma Myeloma Leuk 23:385–393. https://doi.org/10.1016/J.CLML.2023.02.006

5. Engelhardt M, Dold SM, Ihorst G et al (2016) Geriatric assessment in multiple myeloma patients: Validation of the international Myeloma Working Group (IMWG) score and comparison with other common comorbidity scores. Haematologica 101:1110–1119. https://doi.org/10.3324/haematol.2016.148189

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1. In search for cure of multiple myeloma;Haematologica;2023-11-16

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