Dose-dense ABVD as first-line therapy in early-stage unfavorable Hodgkin lymphoma: results of a prospective, multicenter double-step phase II study by Fondazione Italiana Linfomi

Author:

Santoro ArmandoORCID,Mazza Rita,Spina Michele,Califano Catello,Specchia Giorgina,Carella Michele,Consoli Ugo,Palombi Francesca,Musso Maurizio,Pulsoni Alessandro,Kovalchuk Sofya,Bonfichi Maurizio,Ricci Francesca,Fabbri Alberto,Liberati Anna Marina,Rodari Marcello,Giordano Laura,Chimienti Emanuela,Balzarotti Monica,Sorasio Roberto,Gallamini Andrea,Ghiggi Chiara,Ciammella Patrizia,Ricardi Umberto,Chauvie Stephane,Carlo-Stella Carmelo,Merli Francesco

Publisher

Springer Science and Business Media LLC

Subject

Hematology,General Medicine

Reference29 articles.

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2. Fermé C, Eghbali H, Meerwaldt JH, Rieux C, Bosq J, Berger F, Girinsky T, Brice P, van’t Veer MB, Walewski JA, Lederlin P, Tirelli U, Carde P, Van den Neste E, Gyan E, Monconduit M, Diviné M, Raemaekers JM, Salles G, Noordijk EM, Creemers GJ, Gabarre J, Hagenbeek A, Reman O, Blanc M, Thomas J, Vié B, Kluin-Nelemans JC, Viseu F, Baars JW, Poortmans P, Lugtenburg PJ, Carrie C, Jaubert J, Henry-Amar M, EORTC-GELA H8 Trial (2007) Chemotherapy plus involved-field radiation in early-stage Hodgkin’s disease. N Engl J Med 357(19):1916–27. https://doi.org/10.1056/NEJMoa064601

3. Engert A, Schiller P, Josting A, Herrmann R, Koch P, Sieber M, Boissevain F, De Wit M, Mezger J, Duhmke E, Willich N, Muller RP, Schmidt BF, Renner H, Muller-Hermelink HK, Pfistner B, Wolf J, Hasenclever D, Loffler M, Diehl V, German Hodgkin’s Lymphoma Study Group (2003) Involved-field radiotherapy is equally effective and less toxic compared with extended-field radiotherapy after four cycles of chemotherapy in patients with early-stage unfavorable Hodgkin’s lymphoma: results of the HD8 trial of the German Hodgkin’s Lymphoma Study Group. J Clin Oncol 21(19):3601–8. https://doi.org/10.1200/JCO.2003.03.023

4. Borchmann P, Eichenauer DA, Pluetschow A (2015) Targeted BEACOPP variants in patients with newly diagnosed advanced stage classical Hodgkin lymphoma: final analysis of a randomized phase II study. Blood 126:580. https://doi.org/10.1182/blood.V126.23.580.580

5. Hasenclever D, Loeffler M, Diehl V (1996) Rationale for dose escalation of first line conventional chemotherapy in advanced Hodgkin’s disease. German Hodgkin’s Lymphoma Study Group. Ann Oncol 7(Suppl 4):95–98. https://doi.org/10.1093/annonc/7.suppl_4.S95

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