Dose-finding trial of azacitidine as post-transplant maintenance for high-risk MDS: a KSGCT prospective study

Author:

Najima YuhoORCID,Tachibana Takayoshi,Takeda Yusuke,Koda Yuya,Aoyama Yasuhisa,Toya Takashi,Igarashi Aiko,Tanaka Masatsugu,Sakaida Emiko,Abe Ryohei,Onizuka Makoto,Kobayashi Takeshi,Doki Noriko,Ohashi Kazuteru,Kanamori Heiwa,Ishizaki Takuma,Yokota Akira,Morita Satoshi,Okamoto Shinichiro,Kanda Yoshinobu

Publisher

Springer Science and Business Media LLC

Subject

Hematology,General Medicine

Reference32 articles.

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2. Warlick ED, Cioc A, Defor T, Dolan M, Weisdorf D (2009) Allogeneic stem cell transplantation for adults with myelodysplastic syndromes: importance of pretransplant disease burden. Biol Blood Marrow Transplant 15:30–38

3. Mielcarek M, Storer BE, Flowers ME, Storb R, Sandmaier BM, Martin PJ (2007) Outcomes among patients with recurrent high-risk hematologic malignancies after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 13:1160–1168

4. Fenaux P, Mufti GJ, Hellstrom-Lindberg E, Santini V, Finelli C, Giagounidis A, Schoch R, Gattermann N, Sanz G, List A, Gore SD, Seymour JF, Bennett JM, Byrd J, Backstrom J, Zimmerman L, McKenzie D, Beach C, Silverman LR (2009) Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol 10:223–232

5. de Lima M, Giralt S, Thall PF, de Padua SL, Jones RB, Komanduri K, Braun TM, Nguyen HQ, Champlin R, Garcia-Manero G (2010) Maintenance therapy with low-dose azacitidine after allogeneic hematopoietic stem cell transplantation for recurrent acute myelogenous leukemia or myelodysplastic syndrome: a dose and schedule finding study. Cancer 116:5420–5431

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