Detection of circulating tumor DNA in cerebrospinal fluid prior to diagnosis of spinal cord lymphoma by flow cytometric and cytologic analyses

Author:

Iriyama Chisako,Murate Kenichiro,Iba Sachiko,Okamoto Akinao,Yamamoto Hideyuki,Kanbara Ayana,Sato Akane,Iwata Emiko,Yamada Ryuta,Okamoto Masataka,Watanabe Hirohisa,Mutoh Tatsuro,Tomita AkihiroORCID

Funder

Grants-in-Aid from the Ministry of Education, Culture, Sports, Science and Technology, Japan

Publisher

Springer Science and Business Media LLC

Subject

Hematology,General Medicine

Reference8 articles.

1. Rimelen V, Ahle G, Pencreach E, Zinniger N, Debliquis A, Zalmai L, Harzallah I, Hurstel R, Alamome I, Lamy F, Voirin J, Drenou B (2019) Tumor cell-free DNA detection in CSF for primary CNS lymphoma diagnosis. Acta Neuropathol Commun 7(1):43. https://doi.org/10.1186/s40478-019-0692-8

2. Hiemcke-Jiwa LS, Leguit RJ, Snijders TJ, Bromberg JEC, Nierkens S, Jiwa NM, Minnema MC, Huibers MMH (2019) MYD88 p.(L265P) detection on cell-free DNA in liquid biopsies of patients with primary central nervous system lymphoma. Br J Haematol 185(5):974–977. https://doi.org/10.1111/bjh.15674

3. Ferreri AJM, Calimeri T, Lopedote P, Francaviglia I, Daverio R, Iacona C, Belloni C, Steffanoni S, Gulino A, Anghileri E, Diffidenti A, Finardi A, Gagliardi F, Anzalone N, Nonis A, Furlan R, De Lorenzo D, Terreni MR, Martinelli V, Sassone M, Foppoli M, Angelillo P, Guggiari E, Falini A, Mortini P, Filippi M, Tarantino V, Eoli M, Ciceri F, Doglioni C, Tripodo C, Locatelli M, Cangi MG, Ponzoni M (2021) MYD88 L265P mutation and interleukin-10 detection in cerebrospinal fluid are highly specific discriminating markers in patients with primary central nervous system lymphoma: results from a prospective study. Br J Haematol 193(3):497–505. https://doi.org/10.1111/bjh.17357

4. Iriyama C, Tomita A, Hoshino H, Adachi-Shirahata M, Furukawa-Hibi Y, Yamada K, Kiyoi H, Naoe T (2012) Using peripheral blood circulating DNAs to detect CpG global methylation status and genetic mutations in patients with myelodysplastic syndrome. Biochem Biophys Res Commun 419(4):662–669. https://doi.org/10.1016/j.bbrc.2012.02.071

5. Suzuki Y, Tomita A, Nakamura F, Iriyama C, Shirahata-Adachi M, Shimada K, Akashi A, Ishikawa Y, Kaneda N, Kiyoi H (2016) Peripheral blood cell-free DNA is an alternative tumor DNA source reflecting disease status in myelodysplastic syndromes. Cancer Sci 107(9):1329–1337. https://doi.org/10.1111/cas.12994

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