A fast and simple approach for the simultaneous detection of hematopoietic chimerism, NPM1, and FLT3-ITD mutations after allogeneic stem cell transplantation

Author:

Waterhouse Miguel,Bertz Hartmut,Finke Juergen

Publisher

Springer Science and Business Media LLC

Subject

Hematology,General Medicine

Reference22 articles.

1. Serrano J, Roman J, Herrera C, Castillejo JA, Reina ML, Gonzalez MG, Rodriguez MC, Pascual A, Sanchez J, Torres A (1999) Increasing hematopoietic mixed chimerism alter BMT with total depletion of CD4+ and partial depletion of CD8+ lymphocytes is associated with a higher incidence of relapse. Bone Marrow Transplant 23:475–482

2. Bader P, Beck J, Frey A, Schlegel PG, Hebarth H, Handgretinger R, Einsele H, Niemeyer C, Benda N, Faul C, Kanz L, Niethammer D, Klingebiel T (1998) Serial and quantitative analysis of mixed hematopoietic chimerism by PCR in patients with acute leukemias allows the prediction of relapse after allogeneic BMT. Bone Marrow Transplant 21:487–495

3. Schaap N, Schattenberg A, Mensink E, Prejiers F, Hillegers M, Knops R, Pennings A, Boezeman J, Geurts van Kessel A, de Pauw B, de Witte T (2002) Long-term follow up of persisting mixed chimerism after partially T cell depleted allogeneic stem cell transplantation. Leukemia 16:13–21

4. Dey BR, McAfee S, Colby C, Sackestein R, Saidman S, Tarbell N, Sachs DH, Sykes M, Spitzer TR (2003) Impact or prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation. Biol Blood Marrow Transplant 9(5):320–329

5. Zeiser R, Spyridonidis A, Wäsch R, Ihorst G, Grüllich C, Bertz H, Finke J (2005) Evaluation of immunomodulatory treatment based on conventional and lineage-specific chimerism analysis in patients with myeloid malignancies after myeloablative allogeneic hematopoietic cell transplantation. Leukemia 19:814–821

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