Fixed-dose administration and pharmacokinetically guided adjustment of busulfan dose for patients undergoing hematopoietic stem cell transplantation: a meta-analysis and cost-effectiveness analysis

Author:

Chen Tingting,Chen Chaoxin,He Xin,Guo Jianming,Liu Maobai,Zheng Bin

Funder

Fujian Provincial Department of Science and Technology

Joint Funds for the innovation of science and Technology, Fujian province

Publisher

Springer Science and Business Media LLC

Subject

Hematology,General Medicine

Reference29 articles.

1. Pasquini MC, Le-Rademacher J, Zhu X, Artz A, DiPersio J, Fernandez HF et al (2016) Intravenous busulfan-based myeloablative conditioning regimens prior to hematopoietic cell transplantation for hematologic malignancies. Biol Blood Marrow Transplant 22:1424–1430

2. Gaziev J, Nguyen L, Puozzo C, Mozzi AF, Casella M, Perrone Donnorso M et al (2010) Novel pharmacokinetic behavior of intravenous busulfan in children with thalassemia undergoing hematopoietic stem cell transplantation: a prospective evaluation of pharmacokinetic and pharmacodynamic profile with therapeutic drug monitoring. Blood 115(22):4597–4604

3. Lee JH, Choi SJ, Lee JH, Kim SE, Park CJ, Chi HS et al (2005) Decreased incidence of hepatic veno-occlusive disease and fewer hemostatic derangements associated with intravenous busulfan vs oral busulfan in adults conditioned with busulfan + cyclophosphamide for allogeneic bone marrow transplantation. Ann Hematol 84(5):321–330

4. de Lima M, Couriel D, Thall PF, Wang X, Madden T, Jones R et al (2004) Once-daily intravenous busulfan and fludarabine: clinical and pharmacokinetic results of a myeloablative, reduced-toxicity conditioning regimen for allogeneic stem cell transplantation in AML and MDS. Blood 104(3):857–886

5. Palmer J, McCune JS, Perales MA, Marks D, Bubalo J, Mohty M et al (2016) Personalizing busulfan-based conditioning: considerations from the American Society for Blood and Marrow Transplantation Practice Guidelines Committee. Biol Blood Marrow Transplant 22(11):1915–1925

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