Leukemic form of high-grade B-cell lymphoma (HGBL) in a very elderly patient with multiple comorbidities: effective treatment of a very rare subtype with a mini-R-da-EPOCH version

Author:

Belia Marina,Drandakis Ioannis,Lakiotaki Eleftheria,Arapaki Maria,Panitsas Fotios,Triantafyllou Evangelia-Fedra,Plata Eleni,Siakantaris Marina P.,Angelopoulou Maria K.,Korkolopoulou Penelope,Vassilakopoulos Theodoros P.ORCID

Publisher

Springer Science and Business Media LLC

Subject

Hematology,General Medicine

Reference11 articles.

1. Campo E, Jaffe ES, Cook JR, Quintanilla-Martinez L, Swerdlow SH, Anderson KC, Brousset P, Cerroni L, de Leval L, Dirnhofer S, Dogan A, Feldman AL, Fend F, Friedberg JW, Gaulard P, Ghia P, Horwitz SM, King RL, Salles G, San-Miguel J, Seymour JF, Treon SP, Vose JM, Zucca E, Advani R, Ansell S, Au W-Y, Barrionuevo C, Bergsagel L, Chan WC, Cohen JI, d’Amore F, Davies A, Falini B, Ghobrial IM, Goodlad JR, Gribben JG, Hsi ED, Kahl BS, Kim W-S, Kumar S, LaCasce AS, Laurent C, Lenz G, Leonard JP, Link MP, Lopez-Guillermo A, Mateos MV, Macintyre E, Melnick AM, Morschhauser F, Nakamura S, Narbaitz M, Pavlovsky A, Pileri SA, Piris M, Pro B, Rajkumar V, Rosen ST, Sander B, Sehn L, Shipp MA, Smith SM, Staudt LM, Thieblemont C, Tousseyn T, Wilson WH, Yoshino T, Zinzani P-L, Dreyling M, Scott DW, Winter JN, Zelenetz AD (2022) The international consensus classification of mature lymphoid neoplasms: a report from the Clinical Advisory Committee. Blood 140(11):1229–1253

2. Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, Advani R, Ghielmini M, Salles GA, Zelenetz AD, Jaffe ES (2016) The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood 127(20):2375–90. https://doi.org/10.1182/blood-2016-01-643569

3. Peyrade F, Jardin F, Thieblemont C, Thyss A, Emile JF, Castaigne S, Coiffier B, Haioun C, Bologna S, Fitoussi O, Lepeu G, Fruchart C, Bordessoule D, Blanc M, Delarue R, Janvier M, Salles B, André M, Fournier M, Gaulard P, Tilly H, Grouped’Etude des Lymphomes de l’Adulte (GELA) investigators (2011) Attenuated immunochemotherapy regimen (R-miniCHOP) in elderly patients older than 80 years with diffuse large B-cell lymphoma: a multicentre, single-arm, phase 2 trial. Lancet Oncol 12(5):460–8. https://doi.org/10.1016/S1470-2045(11)70069-9

4. Dunleavy K, Pittaluga S, Shovlin M, Steinberg SM, Cole D, Grant C, Widemann B, Staudt LM, Jaffe ES, Little RF, Wilson WH (2013) Low-intensity therapy in adults with Burkitt’s lymphoma. N Engl J Med 369(20):1915–1925. https://doi.org/10.1056/NEJMoa1308392

5. Kuhlman JJ, Moustafa MA, Jiang L, Iqbal M, Seegobin K, Wolcott Z, Ayala E, Ansell S, Rosenthal A, Paludo J, Micallef I, Johnston P, Inwards D, Habermann T, Kharfan-Dabaja M, Witzig TE, Nowakowski GS, Tun HW (2022) Leukemic high grade B cell lymphoma is associated with MYC translocation, double hit/triple hit status, transformation, and CNS disease risk: the Mayo Clinic experience. Clin Lymphoma Myeloma Leuk 22(8):e815–e825. https://doi.org/10.1016/j.clml.2022.04.009

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