Cytogenetically cryptic insertion of PML segment into RARA on chromosome 17q resulting PML-RARA fusion in acute promyelocytic leukemia

Author:

Burns Timothy F.,Loo Eric Y.,Bengtson Elizabeth M.,Bao Liming

Publisher

Springer Science and Business Media LLC

Subject

Hematology,General Medicine

Reference7 articles.

1. Grimwade D, Biondi A, Mozziconacci MJ et al (2000) Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): results of the European Working Party. Groupe Francais de Cytogenetique Hematologique, Groupe de Francais d'Hematologie Cellulaire, UK Cancer Cytogenetics Group and BIOMED 1 European Community-Concerted Action “Molecular Cytogenetic Diagnosis in Haematological Malignancies”. Blood 96(4):1297–1308

2. Grimwade D, Gorman P, Duprez E et al (1997) Characterization of cryptic rearrangements and variant translocations in acute promyelocytic leukemia. Blood 90(12):4876–4885

3. Campbell LJ, Oei P, Brookwell R et al (2013) FISH detection of PML-RARA fusion in ins(15;17) acute promyelocytic leukaemia depends on probe size. Biomed Res Int 2013:164501

4. Blanco EM, Curry CV, Lu XY et al (2014) Cytogenetically cryptic and FISH-negative PML/RARA rearrangement in acute promyelocytic leukemia detected only by PCR: an exceedingly rare phenomenon. Cancer Genet 207(1–2):48–49

5. Lafage-Pochitaloff M, Alcalay M, Brunel V et al (1995) Acute promyelocytic leukemia cases with nonreciprocal PML/RARa or RARa/PML fusion genes. Blood 85(5):1169–1174

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