Does a herniated lumbar disk with nerve root entrapment require surgical intervention: Are alternative treatments as effective?
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11916-998-0055-9.pdf
Reference17 articles.
1. Saal JA: Natural history and nonoperative treatment of lumbar disc herniation. Spine 1996, 21(suppl 24):2S-9S.
2. Yukawa Y, Kato F, Matsubara Y, et al.: Serial magnetic resonance imaging follow-up study of lumbar disc herniation conservatively treated for average 30 months: relation between reduction of herniation and degeneration of disc. J Spinal Disord 1996, 9:251–256. This study found that despite no apparent alteration or diminution of the herniated disk as revealed by MRI, patients often report near or complete resolution of symptoms when managed conservatively.
3. O’Donnell JL, O’Donnell AL: Prostaglandin E2 content in herniated lumbar disc disease. Spine 1996, 21:1653–1665.
4. Takahashi H, Suguro T, Okazima Y, et al.: Inflammatory cytokines in the herniated disc of the lumbar spine. Spine 1996, 21:218–224. Cytokines, among other compounds, may be responsible for many of the symptoms attributable to nerve root compression, since removal of a free fragment disk containing these potentially inflammatory compounds has been shown to result in improvement. However, further studies are needed to clarify the role of inflammatory cytokines in producing sciatica.
5. Colonna P, Friedenberg Z: The disc syndrome. J Bone Joint Surg 1949, 31A:614.
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