New Therapeutic Opportunities Based on DNA Mismatch Repair and BRAF Status in Metastatic Colorectal Cancer-Reference-Cited by-同舟云学术

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New Therapeutic Opportunities Based on DNA Mismatch Repair and BRAF Status in Metastatic Colorectal Cancer

Published:2016-02-10 Issue:3 Volume:18 Page:
ISSN:1523-3790
Container-title:Current Oncology Reports
language:en
Short-container-title:Curr Oncol Rep

Author:

Cohen Romain,Svrcek Magali,Dreyer Chantal,Cervera Pascale,Duval Alex,Pocard Marc,Fléjou Jean-François,de Gramont Aimery,André Thierry

Publisher

Springer Science and Business Media LLC

Subject

Oncology

Link

http://link.springer.com/content/pdf/10.1007/s11912-016-0504-2.pdf

Reference74 articles.

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2. Dienstmann R, Guinney J, Delorenzi M, Reynies AD, Roepman P, Sadanandam A, et al. Colorectal cancer subtyping consortium (CRCSC) identification of a consensus of molecular subtypes. J Clin Oncol. 2014;32(5s). Suppl; abstr 3511.

3. Marisa L, de Reyniès A, Duval A, Selves J, Gaub MP, Vescovo L, et al. Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value. Kemp C, editor. PLoS Med. 2013;10:e1001453.

4. Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, et al. PD-1 blockade in tumors with mismatch-repair deficiency. N Engl J Med. 2015;372:2509–20. MMR deficiency predicts efficacy of immune checkpoint inhibition with PD-1 inhibitor pembrolizumab in colorectal and non-colorectal carcinomas.

5. Dolcetti R, Viel A, Doglioni C, Russo A, Guidoboni M, Capozzi E, et al. High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability. Am J Pathol. 1999;154:1805–13.

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