Benefit and Harms of New Anti-Cancer Drugs
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology
Link
http://link.springer.com/content/pdf/10.1007/s11912-013-0303-y.pdf
Reference34 articles.
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3. •• Niraula S, Seruga B, Ocana A, Shao T, Goldstein R, Tannock IF, et al. The price we pay for progress: a meta-analysis of harms of newly approved anticancer drugs. J Clin Oncol. 2012;30(24):3012–9. Epub 2012/07/18. This meta-analysis showed that newly approved cancer drugs have significantly higher toxicity than control treatments in randomized trials.
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5. Sargent DJ, Wieand HS, Haller DG, Gray R, Benedetti JK, Buyse M, et al. Disease-free survival versus overall survival as a primary end point for adjuvant colon cancer studies: individual patient data from 20,898 patients on 18 randomized trials. J Clin Oncol. 2005;23(34):8664–70. Epub 2005/11/02.
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