Evolving Strategies to Potentially Further Optimize Surgical Interventions in Brain Cancer

Author:

Parikh Bindi B.,Neil Elizabeth C.

Publisher

Springer Science and Business Media LLC

Subject

Oncology

Reference54 articles.

1. • Brachman DG, Youssef E, Dardis CJ, Sanai N, Zabramski JM, Smith KA et al. Resection and permanent intracranial brachytherapy using modular, biocompatible cesium-131 implants: results in 20 recurrent, previously irradiated meningiomas. J Neurosurg. 2018;1–10. https://doi.org/10.3171/2018.7.jns18656. This reference demonstrated that resection and adjuvant brachytherapy using a collagen tile embedded with Cs-131 is both effective and safe in previously irradiated recurrent meningiomas.

2. Brachman D, Youssef E, Dardis C, Smith K, Pinnaduwage D, Nakaji P. Surgically targeted radiation therapy: safety profile of collagen tile brachytherapy in 79 recurrent, previously irradiated intracranial neoplasms on a prospective clinical trial. Brachytherapy. 2019;18(3):S35–S6. https://doi.org/10.1016/j.brachy.2019.04.076.

3. • Youssef E, Nakaji P, Thomas T, McBride H, Fram E, Brachman D. SCDT-36. Novel modular, permanently implanted collagen-based device for intraoperative brachytherapy in patients with central nervous system tumors. Neuro Oncol. 2017;19(Suppl 6):vi272-vi. https://doi.org/10.1093/neuonc/nox168.1117. This reference offers GammaTile as a solution to the challenges of traditional brachytherapy. GammaTile acts as a 3D spacer and multi-seed carrier which enables rapid implantation while preventing seed migration and direct seed-to-brain contact.

4. • Wernicke AG, Smith AW, Taube S, Yondorf MZ, Parashar B, Trichter S, et al. Cesium-131 brachytherapy for recurrent brain metastases: durable salvage treatment for previously irradiated metastatic disease. J Neurosurg. 2017;126(4):1212–9. https://doi.org/10.3171/2016.3.jns152836. This reference demonstrated that intraoperative cesium-131 brachytherapy after resection can be a successful salvage treatment in recurring previously irradiated metastatic brain disease. Results showed that this treatment option offers local control while being safe and well tolerated. The rationale for using Cesium-131 and its role in lowering risk for radionecrosis is also discussed.

5. Armpilia CI, Dale RG, Coles IP, Jones B, Antipas V. The determination of radiobiologically optimized half-lives for radionuclides used in permanent brachytherapy implants. Int J Radiat Oncol Biol Phys. 2003;55(2):378–85. https://doi.org/10.1016/s0360-3016(02)04208-6.

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