Treatment of Rectal Cancer in Older Adults-Reference-Cited by-同舟云学术

Treatment of Rectal Cancer in Older Adults

Published:2018-11-20 Issue:12 Volume:20 Page:
ISSN:1523-3790
Container-title:Current Oncology Reports
language:en
Short-container-title:Curr Oncol Rep

Author:

Sheikh Ayesha R.,Yameen Hassan,Hartshorn Kevan

Publisher

Springer Science and Business Media LLC

Subject

Oncology

Link

http://link.springer.com/article/10.1007/s11912-018-0746-2/fulltext.html

Reference86 articles.

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2. Extermann M, Boler I, Reich R, Lyman GH, Brown RH, DeFelice J, et al. The Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score: Design and validation. J Clin Oncol. 2010.

3. Hurria A, Togawa K, Mohile SG, et al. Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study. J Clin Oncol. 2011. https://doi.org/10.1200/JCO.2011.34.7625 .

4. •• McCleary, NJ, Hubbard J, Mahoney MR, Meyerhardt JA, Sargent D, Venook A, Grothey A. Challenges of conducting a prospective clinical trial for older patients: Lessons learned from NCCTG N0949 (alliance). J Geriatr Oncol. 2018. https://doi.org/10.1016/j.jgo.2017.08.005 . A phase III trial, to evaluate treatment outcome differences in older adults (70 and above) accrued only 32 patients of the projected 380. Reasons for the poor accrual included discomfort with randomizing older adults to regimens of varying intensity without considering their fitness, as well as concerns about bevacizumab use in older adults.

5. Bohac GC, Guaqueta D, Cheng DM, Aschengrau A, Hartshorn KL. Disparity in the use of combined modality therapy for rectal cancer in the older adult. J Geriatr Oncol. 2013. https://doi.org/10.1016/j.jgo.2012.10.173 .

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