Development of Phosphoinositide-3 Kinase Pathway Inhibitors for Advanced Cancer
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology
Link
http://link.springer.com/content/pdf/10.1007/s11912-010-0091-6.pdf
Reference54 articles.
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3. • Liu P, Cheng H, Roberts TM, Zhao JJ: Targeting the phosphoinositide 3-kinase pathway in cancer. Nat Rev Drug Discov 2009, 8:627–644. This article provides an extremely informative review on the role of PI3K in cancer. It also reviews therapeutic approaches of targeting the PI3K pathway.
4. • Marone R, Cmiljanovic V, Giese B, Wymann MP: Targeting phosphoinositide 3-kinase: moving towards therapy. Biochim Biophys Acta 2008, 1784:159–185. This excellent review thoroughly details the development of PI3K inhibitors.
5. Gupta S, Ramjaun AR, Haiko P, Wang Y, et al.: Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice. Cell 2007,129:957–968.
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