Prognostic factors in pediatric Hodgkin disease

Author:

Schwartz Cindy L.

Publisher

Springer Science and Business Media LLC

Subject

Oncology

Reference52 articles.

1. Carbone PP, Kaplan HS, Musshoff K, et al.: Report of the Committee on Hodgkin’s Disease Staging Classification. Cancer Res 1971, 31:1860–1861.

2. Schwartz CL, Tebbi C, Constine LS, et al.: Response-based therapy for pediatric Hodgkin’s disease: Pediatric Oncology Group (POG) Protocols 9425/9426 [abstract]. Med Pediatr Oncol 2001, 37:263.

3. Landman-Parker J, Pacquement H, Leblanc T, et al.: Localized childhood Hodgkin’s disease: response adopted chemotherapy with etoposide, bleomycin, vinblastin, and prednisone before low-dose raditaion therapy: results of the French Society of Pediatric Oncology Study MDH90. J Clin Oncol 2000, 18:1500–1507. This study provides an important proposal for a prognostic system for children and offers a view of the use of response-directed therapy.

4. Zander T, Wiedenmann S, Wolf J: Prognostic factors in Hodgkin’s lymphoma. Ann Oncol 2002, 13(Suppl 1):67–74.

5. Nachman JB, Sposto R, Herzog P, et al.: Randomized comparison of low-dose involved-field radiotherapy and no radiotherapy for children with Hodgkin’s disease who achieve a complete response to chemotherapy. J Clin Oncol 2002, 20:3765–3771. Report from a large randomized trial in pediatric Hodgkin disease assessing the possibility of reducing therapy (eliminating radiation) in those in complete response at the end of therapy. Relapse rates were higher in those who were not irradiated, suggesting that complete response at the end of therapy may not be a sufficiently good prognostic indicator to limit radiotherapy.

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