Aspirin attenuates podocyte injury in diabetic rats through overriding cyclooxygenase-2-mediated dysregulation of LDL receptor pathway

Author:

Ma Kun LingORCID,Liu Liang,Zhang Yang,Wang Gui Hua,Hu Ze Bo,Chen Pei Pei,Lu Jian,Lu Chen Chen,Gong Tie Kai,Gong Yu Xiang,Liu Bi Cheng

Funder

the National Natural Science Foundation of China

the Jiangsu Province Social Development Project

the Jiangsu Province Six Talent Peaks Project

the Project for Jiangsu Provincial Medical Talent

the Fundamental Research Funds for the Central Universities

the Jiangsu Province Ordinary University Graduate Research Innovation Project

the Project of Nanjing Municipal Committee for Health and Family Planning

Publisher

Springer Science and Business Media LLC

Subject

Urology,Nephrology

Reference30 articles.

1. Chen J, Cui W, Zhang Q, Jia Y, Sun Y, Weng L et al (2015) Low molecular weight fucoidan ameliorates diabetic nephropathy via inhibiting epithelial-mesenchymal transition and fibrotic processes. Am J Transl Res 7(9):1553–1563

2. Chen HC, Guh JY, Chang JM, Hsieh MC, Shin SJ, Lai YH (2005) Role of lipid control in diabetic nephropathy. Kidney Int 67(Suppl 94):S60–S62

3. Zhang Y, Ma KL, Ruan XZ, Liu BC (2016) Dysregulation of the low-density lipoprotein receptor pathway is involved in lipid disorder-mediated organ injury. Int J Biol Sci 12(5):569–579

4. Hao CM, Breyer MD (2007) Physiologic and pathophysiologic roles of lipid mediators in the kidney. Kidney Int 71(11):1105–1115

5. Komers R, Lindsley JN, Oyama TT, Schutzer WE, Reed JF, Mader SL et al (2001) Immunohistochemical and functional correlations of renal cyclooxygenase-2 in experimental diabetes. J Clin Invest 107(7):889–898

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