Author:
Shimoi Tatsunori,Nagai Shigenori E.,Yoshinami Tetsuhiro,Takahashi Masato,Arioka Hitoshi,Ishihara Mikiya,Kikawa Yuichiro,Koizumi Kei,Kondo Naoto,Sagara Yasuaki,Takada Masahiro,Takano Toshimi,Tsurutani Junji,Naito Yoichi,Nakamura Rikiya,Hattori Masaya,Hara Fimikata,Hayashi Naoki,Mizuno Toshiro,Miyashita Minoru,Yamashita Nami,Yamanaka Takashi,Saji Shigehira,Iwata Hiroji,Toyama Tatsuya
Abstract
Abstract
Purpose
We present the English version of The Japanese Breast Cancer Society (JBCS) Clinical Practice Guidelines for systemic treatment of breast cancer, 2018 edition.
Methods
The JBCS formed a task force to update the JBCS Clinical Practice Guidelines, 2015 edition, according to Minds Handbook for Clinical Practice Guideline Development 2014. First, we set multiple outcomes for each clinical question (CQ). Next, quantitative or qualitative systematic review was conducted for each of the multiple outcomes, and the strength of recommendation for the CQ was taken into consideration during meetings, with the aim of finding a balance between benefit and harm. Finalized recommendations from each session were confirmed through discussion and voting at the recommendation decision meeting.
Results
The recommendations, the strength of recommendation and the strength of evidence were determined based on systemic literature reviews and the meta-analyses for each CQ.
Conclusion
The JBCS updated the Clinical Practice Guidelines for systemic treatment of breast cancer.
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Radiology, Nuclear Medicine and imaging,Oncology,General Medicine