Abstract
AbstractIncidental basal ganglia calcifications are a common finding on computed tomography (CT). We investigated the histological characteristics of these calcifications and their association with CT findings, using post-mortem basal ganglia tissue from 22 patients. Eight patients had basal ganglia calcifications on histology, and six patients had calcifications on CT, varying from mild to severe. Four patients had calcifications identified by both histology and CT, and two patients had calcifications detected by CT but not by histology, possibly because of insufficient tissue available. Calcifications were found mainly in the tunica media of arterioles located in the globus pallidus, which suggests that incidental CT calcifications are vascular in nature. However, tunica media calcifications, and thereby incidental basal ganglia calcifications, are probably not related to atherosclerosis.
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine,Clinical Neurology,Radiology Nuclear Medicine and imaging
Reference10 articles.
1. Fritzsche R (1924) Eine familiar auftrentende From vonolidophrenie mit vontgenologish nachveisbaren symmetrischein Kalkoablagerungenim Geheirn besounders in den Stammganglien Schweiz. Arch Neurol Neurochir Psychiatr 1:29–33
2. Simoni M, Pantoni L, Pracucci G, Palmertz B, Guo X, Gustafson D, Skoog I (2008) Prevalence of CT-detected cerebral abnormalities in an elderly Swedish population sample. Acta Neurol Scand 118:260–267
3. Koller WC, Cochran JW, Klawans HL (1979) Calcification of the basal ganglia: computerized tomography and clinical correlation. Neurology 29:328–333
4. De Brouwer EJM, Kockelkoren R, De Vis JB, Dankbaar JW, Velthuis BK, Takx RAP, De Jonghe A, Emmelot-Vonk MH, Koek HL, De Jong PA (2020) Prevalence and vascular risk factors of basal ganglia calcifications in patients at risk for cerebrovascular disease. JNeuroradiol 47:339–344. https://doi.org/10.1016/j.neurad.2019.04.002
5. Ostling S, Andreasson LA, Skoog I (2003) Basal ganglia calcification and psychotic symptoms in the very old. Int J Geriatr Psychiatry 18:983–987
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献