CYP2C19 Genotype-Guided Antiplatelet Therapy in Stroke Patients—Is It Ready for Prime Time?
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Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s10557-024-07627-4.pdf
Reference9 articles.
1. Kleindorfer DO, Towfighi A, Chaturvedi S, et al. 2021 guideline for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline from the American Heart Association/American Stroke Association. Stroke. 2021;52(7):e364–467.
2. McDermott JH, Leach M, Sen D, et al. The role of CYP2C19 genotyping to guide antiplatelet therapy following ischemic stroke or transient ischemic attack. Expert Rev Clin Pharmacol. 2022;15(7):811–25.
3. Klein MD, Williams AK, Lee CR, Stouffer GA. Clinical utility of CYP2C19 genotyping to guide antiplatelet therapy in patients with an acute coronary syndrome or undergoing percutaneous coronary intervention. Arterioscler Thromb Vasc Biol. 2019;39:647–52.
4. Pan Y, Chen W, Xu Y, et al. Genetic polymorphisms and clopidogrel efficacy for acute ischemic stroke or transient ischemic attackclinical perspective: a systematic review and meta-analysis. Circulation. 2017;135(1):21–33.
5. Cargnin S, Ferrari F, Terrazzino S. Impact of CYP2C19 genotype on efficacy and safety of clopidogrel-based antiplatelet therapy in stroke or transient ischemic attack patients: an updated systematic review and meta-analysis of non-east Asian studies. Cardiovasc Drugs Ther. 2023;1–11.
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