Metabolic activation of chemical carcinogens by hepatic preparations from streptozotocin-treated rats

Author:

Flatt P. R.,Bass S. L.,Ayrton A. D.,Trinick J.,Ioannides C.

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference30 articles.

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2. Ryan DE, Thomas PE, Reik LM, Levin W (1982) Purification, characterization and regulation of five rat hepatic cytochrome P450 isozymes. Xenobiotica 12: 727?744

3. Guengerich FP, Dannan GA, Wright ST, Martin MV, Keminsky LS (1982) Purification and characterization of liver microsomal cytochrome P450: electrophoretic, spectral, catalytic and immunochemical properties and inducibility of eight isozymes isolated from animals treated with phenobarbital or ?-naphthoflavone. Biochemistry 26: 1406?1412

4. Ioannides C, Lum PY, Parke DV (1984) Cytochrome P448 and the activation of toxic chemicals and carcinogens. Xenobiotica 14: 119?137

5. Ioannides C, Parke DV (1987) The cytochromes P-448 ? a unique family of enzymes involved in chemical toxicity and carcinogenesis. Biochem Pharm 36: 4197?4207

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