Dosage adjustment in obese children, even for common drugs, is largely unclear and a treat-to-effect approach may work best
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical)
Link
https://link.springer.com/content/pdf/10.1007/s40267-020-00734-w.pdf
Reference60 articles.
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2. American Academy of Pediatrics. Council on child and adolescent health: age limit of pediatrics. Pediatrics. 1988;81(5):736.
3. Harskamp-van Ginkel MW, Hill KD, Becker KC, et al. Drug dosing and pharmacokinetics in children with obesity: a systematic review. JAMA Pediatr. 2015;169(7):678–85.
4. Callaghan LC. Prescribing in paediatric obesity: methods to improve dosing safety in weight-based dose calculations. Arch Dis Child Educ Pract. 2018;103(5):274–7.
5. Anderson BJ, Holford NH. What is the best size predictor for dose in the obese child? Paediatr Anaesth. 2017;27(12):1176–84.
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