Adjust therapy for restless legs syndrome if symptoms worsen, efficacy is lost or iatrogenic augmentation develops
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical)
Link
http://link.springer.com/content/pdf/10.1007/s40267-015-0255-4.pdf
Reference16 articles.
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3. Tzonova D, Larrosa O, Calvo E, et al. Breakthrough symptoms during the daytime in patients with restless legs syndrome (Willis-Ekbom disease). Sleep Med. 2012;13(2):151–5.
4. Allen RP, Earley CJ. Augmentation of the restless legs syndrome with carbidopa/levodopa. Sleep. 1996;19(3):205–13.
5. Högl B, García-Borreguero D, Kohnen R, et al. Progressive development of augmentation during long-term treatment with levodopa in restless legs syndrome: results of a prospective multicenter study. J Neurol. 2010;257(2):230–7.
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1. Consider using opioids to treat restless legs syndrome in patients who have become refractory or intolerant to other treatments;Drugs & Therapy Perspectives;2018-02-28
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